A Study of the Effect of Pregnancy on Hematological Parameters, Kidney and Liver Functions Among Women Attending General Ubari Hospital, Ubari, Libya

Abstract

This study was conducted to investigate the effect of pregnancy trimesters on some hematological parameters, kidney, and liver functions among women attending General Ubari Hospital, Ubari. Libya. The study included 90 pregnant women (aged 15-45 years) in the period from 1 May to 30 May 2022. They were divided into three groups, 30 pregnant women in each group according to pregnancy trimester, and after taking clinical information through the questionnaire, blood samples were taken and a complete blood count (CBC) test was performed, and GPT, GOT, ALP, Urea, Creatinin, Total Protien, Total Bilirubin, and Direct Bilirubin were measured. The results showed that there were statistically significant differences in hemoglobin, hematocrit, and the mean corpuscular hemoglobin concentration and white blood cells in the first trimester of pregnancy compared to the second trimester of pregnancy, with an increase in the number of platelets in the second trimester. As for liver enzyme tests, an increase was observed in the liver enzyme ALP in the first trimester compared with the second trimester, and also in the second trimester compared to the third trimester with statistically significant differences (P<0.05). In regard to creatinine concentration in the first and second trimester, the results showed significant differences between the two trimesters (P=0.0004). The results of Total protein and bilirubin did not show any significant differences. Through this study, it was shown that pregnancy has an effect on some parameters, with a decrease in the concentration of hemoglobin and platelets, an increase in white blood cells count, a decrease in some liver enzymes, and a significant increase in ALP and creatinine.